Bayesian latent class models for identifying canine visceral leishmaniosis using diagnostic tests in the absence of a gold standard.
BackgroundLike many infectious diseases, there is no practical gold standard for diagnosing clinical visceral leishmaniasis (VL).Latent class modeling has been proposed to estimate a latent gold standard for identifying disease.These proposed models for VL have leveraged information from diagnostic tests with dichotomous serological and PCR assays,